Ac-Asp-Glu-Val-Asp-AMC

Ac-Asp-Glu-Val-Asp-AMC is a fluorogenic substrate used to study the activity of caspases, with a peptide sequence that is cleaved to release AMC. The peptide is often used to monitor apoptosis and cell death pathways in vitro. Researchers apply it in studies of protease activity, particularly in the context of apoptosis and cellular stress responses.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Ac-Asp-Glu-Val-Asp-AMC(CAS 169332-61-0)

CAT No: C11071

CAS No:169332-61-0

Synonyms/Alias:Ac-DEVD-AMC;169332-61-0;Ac-Asp-Glu-Val-Asp-AMC ammonium salt;CPP32/Apopain Substrate;Ac-Asp-Glu-Val-Asp-AMC;N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin;(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid;Ac-DEVD-AMC ammonium salt;acetyl-Asp-Glu-Val-Asp-AMC;SCHEMBL1552674;ALZSTTDFHZHSCA-RNVDEAKXSA-N;CASPASE 1 SUBSTRATE (ICE);HY-P1003;MFCD00671411;AKOS040744025;CS-7679;NCGC00485360-01;(4S)-4-{[(1S)-1-{[(1S)-2-carboxy-1-[(4-methyl-2-oxochromen-7-yl)carbamoyl]ethyl]carbamoyl}-2-methylpropyl]carbamoyl}-4-[(2S)-3-carboxy-2-acetamidopropanamido]butanoic acid;BP-23698;DA-70474;FA110568;MS-31067;G12620;acetyl-Asp-Glu-Val-Asp-4-methyl-coumaryl-7-amide;Caspase-3 Substrate II, Fluorogenic - CAS 169332-61-0;N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin, >=97% (HPLC), powder;L-a-Asparagine,N-acetyl-L-a-aspartyl-L-a-glutamyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C30H37N5O13
M.W/Mr.
675.6
Sequence
One Letter Code:DEVD
Three Letter Code:Ac-Asp-Glu-Val-Asp-AMC
InChI
InChI=1S/C30H37N5O13/c1-13(2)26(35-27(44)18(7-8-22(37)38)33-29(46)19(11-23(39)40)31-15(4)36)30(47)34-20(12-24(41)42)28(45)32-16-5-6-17-14(3)9-25(43)48-21(17)10-16/h5-6,9-10,13,18-20,26H,7-8,11-12H2,1-4H3,(H,31,36)(H,32,45)(H,33,46)(H,34,47)(H,35,44)(H,37,38)(H,39,40)(H,41,42)/t18-,19-,20-,26-/m0/s1
InChI Key
ALZSTTDFHZHSCA-RNVDEAKXSA-N

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