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Ac-Asp-Glu-Val-Asp-pNA

Ac-Asp-Glu-Val-Asp-pNA is a fluorogenic substrate used to monitor protease activity, especially in caspase assays. The peptide sequence incorporates an Asp-Glu-Val-Asp recognition site, which is cleaved by proteases to release a chromogenic signal. Researchers use this substrate to investigate cell apoptosis and protease activity in live-cell assays. Its properties make it ideal for high-throughput screening of enzymatic inhibitors.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Ac-Asp-Glu-Val-Asp-pNA(CAS 189950-66-1)

CAT No: C11072

CAS No:189950-66-1

Synonyms/Alias:Ac-DEVD-pNA;189950-66-1;Ac-Asp-Glu-Val-Asp-PNA;N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide;MFCD00792707;(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid;Z-VDVAD-pNA?;N-Acetyl-Asp-Glu-Val-Asp-pna;SCHEMBL2028887;GGXRLUDNGFFUKI-ORGXJRBJSA-N;Ac-DEVD-pNA(Caspase-3 Substrate)?;HY-W338079;N-acetyl-asp-glu-val-asp-p-nitroanilide;(4S,7S,10S,13S)-7-(2-carboxyethyl)-4-(carboxymethyl)-10-isopropyl-13-(4-nitrophenylcarbamoyl)-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid;BP-23537;CS-0449396;A12192;N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide, >=97% (HPLC), powder;L-Asparagine,N-acetyl-L-a-aspartyl-L-a-glutamyl-L-valyl-N-(4-nitrophenyl)-(9CI);

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C26H34N6O13
M.W/Mr.
638.6
Sequence
One Letter Code:DEVD
Three Letter Code:Ac-Asp-Glu-Val-Asp-pNA
InChI
InChI=1S/C26H34N6O13/c1-12(2)22(26(43)30-18(11-21(38)39)24(41)28-14-4-6-15(7-5-14)32(44)45)31-23(40)16(8-9-19(34)35)29-25(42)17(10-20(36)37)27-13(3)33/h4-7,12,16-18,22H,8-11H2,1-3H3,(H,27,33)(H,28,41)(H,29,42)(H,30,43)(H,31,40)(H,34,35)(H,36,37)(H,38,39)/t16-,17-,18-,22-/m0/s1
InChI Key
GGXRLUDNGFFUKI-ORGXJRBJSA-N

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