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Ac-Leu-pNA

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Ac-Leu-pNA(CAS 19746-40-8)

CAT No: CP26606

CAS No: 19746-40-8

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cGMP Peptide

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IND and NDA support Drug master files (DMF) filing

Synonyms/Alias19746-40-8;N-Acetyl-L-leucine-p-nitroanilide;Ac-Leu-pNA;Acetyl-L-leucine 4-nitroanilide;(2S)-2-acetamido-4-methyl-N-(4-nitrophenyl)pentanamide;(S)-2-Acetamido-4-methyl-N-(4-nitrophenyl)pentanamide;DTXSID60428584;N-Acetyl-L-leucine P-nitroanilide;DTXCID30379418;AKOS015909056;FD21915;FA110696;Pentanamide, 2-(acetylamino)-4-methyl-N-(4-nitrophenyl)-, (2S)-;Pentanamide,2-(acetylamino)-4-methyl-N-(4-nitrophenyl)-,(2S)-;
M.F/FormulaC14H19N3O4
M.W/Mr.293.32
SequenceOne Letter Code:L
Three Letter Code:Ac-Leu-pNA
Size1 g;5 g;
InChIInChI=1S/C14H19N3O4/c1-9(2)8-13(15-10(3)18)14(19)16-11-4-6-12(7-5-11)17(20)21/h4-7,9,13H,8H2,1-3H3,(H,15,18)(H,16,19)/t13-/m0/s1
InChI KeySLJKQHDBYBGOMH-ZDUSSCGKSA-N
Canonical SMILESCC(C)CC(C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C
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    Icatibant (Firazyr) is a synthetic peptidomimetic drug consisting of ten amino acids, and acts as an effective and specific antagonist of bradykinin B2 receptors. It has been approved in the EU for use in hereditary angioedema, and is under investigation for a number of other conditions in which bradykinin is thought to play a significant role.

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