Ac-Nle-Pro-Nle-Asp-AMC

Ac-Nle-Pro-Nle-Asp-AMC is a fluorogenic peptide featuring norleucine-rich hydrophobic segments and a proline-induced kink. The AMC group enables detection of proteolytic cleavage through fluorescence release. Its sequence supports mapping of substrate-specificity determinants. Applications include enzymology, kinetic profiling, and structure-activity studies.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: P6308

Synonyms/Alias:Ac-Nle-Pro-Nle-Asp-AMC;355140-49-7;(3S)-3-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamidohexanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-4-[(4-methyl-2-oxochromen-7-yl)amino]-4-oxobutanoic acid;MFCD02259625;HY-P2016;DA-50175;FA110588;MS-30987;CS-0107262;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C33H45N5O9
M.W/Mr.
655.7
Sequence
One Letter Code:XPXD
Three Letter Code:Ac-Nle-Pro-Nle-Asp-AMC
InChI
InChI=1S/C33H45N5O9/c1-5-7-10-23(36-32(45)26-12-9-15-38(26)33(46)24(11-8-6-2)34-20(4)39)30(43)37-25(18-28(40)41)31(44)35-21-13-14-22-19(3)16-29(42)47-27(22)17-21/h13-14,16-17,23-26H,5-12,15,18H2,1-4H3,(H,34,39)(H,35,44)(H,36,45)(H,37,43)(H,40,41)/t23-,24-,25-,26-/m0/s1
InChI Key
WPTAROWBMZVECB-CQJMVLFOSA-N

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