Ac-Tyr-Val-Ala-Asp-AFC is a fluorogenic substrate designed for measuring protease-mediated cleavage events. Its AFC group enables sensitive detection of enzymatic activity through emission-based assays. Researchers employ it to quantify catalytic efficiency and substrate preference. The peptide supports high-throughput profiling of proteolytic mechanisms.
CAT No: C11034
CAS No:219137-85-6
Synonyms/Alias:Ac-YVAD-AFC;219137-85-6;Ac-Tyr-Val-Ala-Asp-AFC;N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin;(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-oxo-4-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]butanoic acid;MFCD01318881;SCHEMBL5888824;CHEBI:136755;GWKJISJKNKIJNP-DEQDFGQZSA-N;HY-P2377;Ac-L-Tyr-L-Val-L-Ala-L-Asp-AFC;AS-86312;DA-50215;CS-0133617;Ac-Tyr-Val-Ala-Asp-7-Amino-4-trifluoromethylcoumarin;N-Acetyl-Tyr-Val-Ala-Asp-7-amino-4-(trifluoromethyl)coumarin;Caspase-1 substrate (fluorogenic), Caspase-4 substrate (fluorogenic);N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin, >=95% (HPLC), powder;N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine;
3. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
4. Emu oil in combination with other active ingredients for treating skin imperfections
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