Ac-Tyr-Val-Ala-Asp-chloromethylketone is an irreversible peptide inhibitor used to interrogate protease catalytic domains. Its reactive group forms covalent complexes for mapping active-site geometry. Researchers apply it to investigate enzyme specificity and structural constraints. The molecule aids development of targeted inhibitory frameworks.
CAT No: C11021
CAS No:178603-78-6
Synonyms/Alias:Ac-YVAD-CMK;178603-78-6;Caspase-1 Inhibitor II;Ac-Tyr-Val-Ala-Asp-chloromethylketone;acetyl-Tyr-Val-Ala-Asp-chloromethylketone;L-Alaninamide, N-acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-;(4S,7S,10S,13S)-13-(2-chloroacetyl)-4-(4-hydroxybenzyl)-7-isopropyl-10-methyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid;N-acetyl-tyr-val-ala-asp-chloromethyl ketone;(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-5-chloro-4-oxopentanoic acid;Ac-Tyr-Val-Ala-Asp-chloromethyl ketone;Ac-Tyr-Val-Ala-Asp-chloromethyl-ketone;acetyl-Tyr-Val-Ala-Asp chloromethylketone;N-Ac-Tyr-Val-Ala-Asp-chloromethyl ketone;acetyl-Tyr-Val-Ala-Asp chloromethyl ketone;acetyl-Tyr-Val-Ala-Asp-chloromethyl ketone;Caspase-1 Inhibitor II;;Caspase 1 Inhibitor II;Ac-Tyr-Val-Ala-Asp-CMK;Ac-YVAD-CMK; N-Acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-L-alaninamide;MFCD00237124;Ac-YVAD-cmk?;N-acetyltyrosinylvalinylalanylaspartylchloromethyl ketone;SCHEMBL18087495;n-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone;Ac-Tyr-Ala-Asp-Chloromethylketone;CHEBI:230455;UOUBHJRCKHLGFB-DGJUNBOTSA-N;BDBM513203;N-acetyl-tyrosinyl-valinyl-alanyl-aspartyl chloromethyl ketone;acs.jmedchem.1c00409_ST.801;EX-A6262;Ac-YVAD-cmk, >=95% (HPLC);AKOS040755207;Ac-Tyr-Val-Ala-Asp chloromethyl ketone;DA-51610;FA111035;HY-16990;MS-29969;acetyl-Tyr-Val-Ala-Asp-chloromethyl-ketone;CS-0013353;N-Acetyl-Tyr-Val-Ala-Asp chloromethyl ketone;Ac-L-Tyr-L-Val-L-Ala-L-Asp-chloromethylketone;E75500;Caspase-1 Inhibitor II - CAS 178603-78-6;N-acetyl-L-tyrosyl-L-valyl-N-[(2S)-1-carboxy-4-chloro-3-oxobutan-2-yl]-L-alaninamide;(3S)-5-CHLORO-3-[(2S)-2-[(2S)-2-[(2S)-2-ACETAMIDO-3-(4-HYDROXYPHENYL)PROPANAMIDO]-3-METHYLBUTANAMIDO]PROPANAMIDO]-4-OXOPENTANOIC ACID;
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