Acetyl Tetrapeptide-5 is a synthetic peptide composed of four amino acids, designed for use in cosmetic formulations targeting the eye contour area. Recognized for its ability to support skin conditioning and hydration, this ingredient is commonly incorporated into products aimed at improving the appearance of puffiness and visible fatigue. Acetyl Tetrapeptide-5 is suitable for inclusion in a variety of topical applications, including serums, gels, and creams.
CAT No: CPC1610
CAS No:820959-17-9
Synonyms/Alias:Acetyl tetrapeptide-5;820959-17-9;Ac-Beta-Ala-His-Ser-His-OH;Eyeseryl;N-Acetyl-beta-alanyl-L-histidyl-L-seryl-L-histidine;UNII-Y1DFQ308G8;Y1DFQ308G8;DTXSID10231560;(3-acetamidopropanoyl)-L-histidyl-L-seryl-L-histidine;(2S)-2-[[(2S)-2-[[(2S)-2-(3-acetamidopropanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid;MFCD30179524;Ac-betaAla-His-Ser-His;DTXCID40154051;EX-A3744;HY-P0095;ACETYL TETRAPEPTIDE-5 [INCI];AKOS030528648;AKOS040751763;DS-19564;DB-221578;CS-0017926;C76631;Q27294139;L-Histidine, N-acetyl-beta-alanyl-L-histidyl-L-seryl-;(2S)-2-[(2S)-2-[(2S)-2-(3-acetamidopropanamido)-3-(1H-imidazol-4-yl)propanamido]-3-hydroxypropanamido]-3-(1H-imidazol-4-yl)propanoic acid;
Mechanism of Action (MOA)
Acetyl Tetrapeptide-5 is a synthetic tetrapeptide that interacts with skin cells by modulating cellular signaling pathways associated with water homeostasis and extracellular matrix components. It is known to influence the expression of aquaporin channels and glycosaminoglycan turnover, supporting optimal skin hydration. Additionally, this peptide may help regulate enzymatic activity involved in tissue equilibrium, contributing to the maintenance of skin's natural appearance and resilience.
Acetyl Tetrapeptide-5 is suitable for incorporation into various cosmetic formulations targeting the eye area and skin hydration. Typical application directions include:
- Add to eye creams and serums during the cooling phase below 40°C- Incorporate into facial gels and lotions for enhanced skin conditioning- Use in sheet masks designed for the periorbital region- Blend into hydrating sprays and mists- Compatible with water-based emulsions and gel systems
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