ADWX 1

Potent and selective KV1.3 channel blocker (IC50 values are 0.0019 and 0.65 nM for KV1.3 and KV1.1, respectively). Inhibits CD4+ CCR7- T cell activation. It is a useful tool for studying the structure-function of Kv1.3 channel and auto-immunity pathways.

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CAT#R1063
M.F/FormulaC169H281N57O46S7
M.W/Mr.4071.86
SequenceVGINVKCKHSRQCLKPCKDAGMRFGKCTNGKCHCTPK(Modifications: Disulfide bridge: 7 - 27, 13 - 32, 17 - 34)
Labeling TargetPotassium channel
AppearanceWhite lyophilised solid
Purity>98%
ActivityBlocker
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