(Ala11.22.28)-VIP (human, mouse, rat) is a vasoactive intestinal peptide analog with alanine substitutions at three key positions, reducing side-chain complexity. The modifications allow examination of structural tolerance within the VIP helix. Its behavior reveals which residues are essential for receptor activation versus structural support. Researchers employ it to map functionally critical sites in VIP signaling.
2. Implications of ligand-receptor binding kinetics on GLP-1R signalling
3. Urinary Metabolites Associated with Blood Pressure on a Low-or High-Sodium Die
4. Myotropic activity of allatostatins in tenebrionid beetles
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