α-amino-2-cyclopentenylacetic acid is a non-proteinogenic amino acid featuring an α-amino and a carboxyl functional group attached to a methylene that links to a cyclopentene side chain, providing a cyclic, unsaturated hydrophobic motif. The molecule bears a primary amino group and a carboxylic acid, and the side chain's alkene enables chemical derivatization routes such as electrophilic addition or cycloaddition chemistry while maintaining the amino acid backbone for peptide-related incorporation. In synthetic and chemical biology workflows, it is used as a building block for preparing structurally defined peptides and amino acid analogues, as well as for structure-activity studies and analytical labeling strategies that require a cyclopentenyl handle.
CAT No: CP20001
3. The spatiotemporal control of signalling and trafficking of the GLP-1R
4. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
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