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Angstrom6

Angstrom6 is a urokinase inhibitor potentially for the treatment of chronic lymphocytic leukemia.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Angstrom6(CAS 220334-14-5)

CAT No: R1929

CAS No:220334-14-5

Synonyms/Alias:A-6 peptide; A-6; A6; A 6

Chemical Name:(S)-4-((S)-1-(acetyl-L-lysyl-L-prolyl-L-seryl-L-seryl-L-prolyl)pyrrolidine-2-carboxamido)-5-(((S)-4-amino-1-carboxy-4-oxobutyl)amino)-5-oxopentanoic acid

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C39H62N10O15
M.W/Mr.
910.98
Sequence
One Letter Code: KPSSPPEQ
Three Letter Code: Ac-Lys-Pro-Ser-Ser-Pro-Pro-Glu-Gln-OH
Application
Chronic Lymphocytic Leukemia
Appearance
Solid powder
Activity
Inhibitor
Long-term Storage Conditions
Soluble in DMSO
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
InChI
InChI=1S/C39H62N10O15/c1-21(52)42-23(7-2-3-15-40)36(60)47-16-4-8-27(47)35(59)45-25(19-50)33(57)46-26(20-51)37(61)49-18-6-10-29(49)38(62)48-17-5-9-28(48)34(58)43-22(12-14-31(54)55)32(56)44-24(39(63)64)11-13-30(41)53/h22-29,50-51H,2-20,40H2,1H3,(H2,41,53)(H,42,52)(H,43,58)(H,44,56)(H,45,59)(H,46,57)(H,54,55)(H,63,64)/t22-,23-,24-,25-,26-,27-,28-,29-/m0/s1
InChI Key
YUDSEXRLRQZDOS-PJYAFMLMSA-N
Canonical SMILES
CC(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(CO)C(=O)NC(CO)C(=O)N2CCCC2C(=O)N3CCCC3C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)O
Isomeric SMILES
CC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N2CCC[C@H]2C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)O

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