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Fluorescent Substrate for Glu-Specific Proteases

Anthranilyl-Ala-Phe-Ala-Phe-Glu-Val-Phe-nitro-Tyr-Asp is a dual-labeled peptide containing an anthranilamide donor and nitrotyrosine acceptor for FRET-based protease assays. The sequence presents multiple hydrophobic and acidic residues shaping substrate specificity. Researchers monitor fluorescence changes to study cleavage patterns and enzyme selectivity. Applications include substrate engineering, detailed kinetic profiling, and protease-substrate mapping.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Fluorescent Substrate for Glu-Specific Proteases(CAS 143147-75-5)

CAT No: R2551

CAS No:143147-75-5

Synonyms/Alias:Anthranilyl-Ala-Phe-Ala-Phe-Glu-Val-Phe-nitro-Tyr-Asp;Fluorescent Substrate for Glu-Specific Proteases;143147-75-5;GGFWDXWGSVJEBX-XMJIKGBQSA-N;HY-P3949;CS-0634383;Anthranilyl-Ala-Phe-Ala-Phe-Glu-Val-Phe-nitro-Tyr-Asp;ANTHRANILYL-ALA-PHE-ALA-PHE-GLU-VAL-PHE- NITRO-TYR-;630-812-6;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C63H73N11O18
M.W/Mr.
1272.3
Sequence
One Letter Code:XAFAFEVFXD
Three Letter Code:H-2Abz-Ala-Phe-Ala-Phe-Glu-Val-Phe-Tyr(3-NO2)-Asp-OH
InChI
InChI=1S/C63H73N11O18/c1-34(2)53(62(88)71-46(30-39-20-12-7-13-21-39)60(86)70-47(61(87)72-48(63(89)90)33-52(78)79)31-40-24-26-50(75)49(32-40)74(91)92)73-57(83)43(25-27-51(76)77)67-59(85)45(29-38-18-10-6-11-19-38)69-55(81)36(4)66-58(84)44(28-37-16-8-5-9-17-37)68-54(80)35(3)65-56(82)41-22-14-15-23-42(41)64/h5-24,26,32,34-36,43-48,53,75H,25,27-31,33,64H2,1-4H3,(H,65,82)(H,66,84)(H,67,85)(H,68,80)(H,69,81)(H,70,86)(H,71,88)(H,72,87)(H,73,83)(H,76,77)(H,78,79)(H,89,90)/t35-,36-,43-,44-,45-,46-,47-,48-,53-/m0/s1
InChI Key
GGFWDXWGSVJEBX-XMJIKGBQSA-N

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