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(Arg)9 TFA

(Arg)9 TFA (Nona-L-arginine TFA), a cell-penetrating peptide, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R1970

CAS No:2283335-13-5

Synonyms/Alias:(Arg)9 TFA salt;2283335-13-5;1228255-42-2;(Arg)9 (trifluoroacetate salt);Nonaarginine, H(-Arg)9-OH, (Arg)9 Trifluoroacetate;(Arg)9 TFA;MFCD08458590;(Arg)9 trifluoroacetate;AKOS040763889;DA-69122;TS-10289;(Arg)9 TFA (143413-47-2 free base);G67569;

Custom Peptide Synthesis
cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C56H111F3N36O12
M.W/Mr.
1537.7
Sequence
One Letter Code:RRRRRRRRR
Three Letter Code:H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH.TFA
Appearance
white solid powder
Long-term Storage Conditions
Soluble in DMSO, not in water
InChI
InChI=1S/C54H110N36O10.C2HF3O2/c55-28(10-1-19-74-46(56)57)37(91)83-29(11-2-20-75-47(58)59)38(92)84-30(12-3-21-76-48(60)61)39(93)85-31(13-4-22-77-49(62)63)40(94)86-32(14-5-23-78-50(64)65)41(95)87-33(15-6-24-79-51(66)67)42(96)88-34(16-7-25-80-52(68)69)43(97)89-35(17-8-26-81-53(70)71)44(98)90-36(45(99)100)18-9-27-82-54(72)73;3-2(4,5)1(6)7/h28-36H,1-27,55H2,(H,83,91)(H,84,92)(H,85,93)(H,86,94)(H,87,95)(H,88,96)(H,89,97)(H,90,98)(H,99,100)(H4,56,57,74)(H4,58,59,75)(H4,60,61,76)(H4,62,63,77)(H4,64,65,78)(H4,66,67,79)(H4,68,69,80)(H4,70,71,81)(H4,72,73,82);(H,6,7)/t28-,29-,30-,31-,32-,33-,34-,35-,36-;/m0./s1
InChI Key
XGQPDCDNEZIVKJ-MXIXLHBGSA-N
Canonical SMILES
CC1=CC(=NN1)NC2=NN3C(=C(N=C3C(=C2)CN4CCOCC4)C)CC5=C(C=C(C=C5)Cl)F

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