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BIM 189

BIM 189 acts as bombesin antagonist that reduces bombesin-induced satiety.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R0869

CAS No:142062-55-3

Synonyms/Alias:[D-Phe6,Leu13,Cpa14]bombesin-(6-14)NH2

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C56H73ClN14O10
M.W/Mr.
1137.73
Sequence
H-D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-Phe(4-Cl)-NH2
Labeling Target
Vombesin
Appearance
White lyophilised solid
Purity
>96%
Activity
Antagonist
Solubility
-20°C
InChI
InChI=1S/C56H73ClN14O10/c1-30(2)21-43(54(79)68-42(49(60)74)23-34-15-17-36(57)18-16-34)69-55(80)45(25-37-27-61-29-64-37)66-47(73)28-63-56(81)48(31(3)4)71-50(75)32(5)65-53(78)44(24-35-26-62-40-14-10-9-13-38(35)40)70-52(77)41(19-20-46(59)72)67-51(76)39(58)22-33-11-7-6-8-12-33/h6-18,26-27,29-32,39,41-45,48,62H,19-25,28,58H2,1-5H3,(H2,59,72)(H2,60,74)(H,61,64)(H,63,81)(H,65,78)(H,66,73)(H,67,76)(H,68,79)(H,69,80)(H,70,77)(H,71,75)/t32-,39+,41-,42-,43-,44-,45-,48-/m0/s1
InChI Key
XJWMPWLZAVKSPK-UYBYNCNQSA-N
Isomeric SMILES
C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC2=CC=C(C=C2)Cl)C(=O)N)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H](CC5=CC=CC=C5)N
BoilingPoint
1600.4ºC at 760mmHg
Melting Point
N/A

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