BMAP-27

Bovine myeloid antimicrobial peptide-27(BMAP-27) belongs to the cathelicidin family of peptides which displays rapid bactericidal activity against Staphylococcus aureus, Streptococcus uberis, and Escherichia coli1. Cathelicidins belong to the large group of cationic peptides with amphipathic properties and have critical role in mammalian innate immune system. BMAP-27 is cytotoxic to human erythrocytes and neutrophils, although at higher than microbicidal concentrations1-2. It has a potential for the treatment of bacterial infections in individuals with cystic fibrosis-associated lung infections.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: AF3342

Synonyms/Alias:Bovine myeloid antimicrobial peptide-27

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M.W/Mr.
3283.3
Sequence
One Letter Code: GRFKRFRKKFKKLFKKLSPVIPLLHLG
Three Letter Code: H-Gly-Arg-Phe-Lys-Arg-Phe-Arg-Lys-Lys-Phe-Lys-Lys-Leu-Phe-Lys-Lys-Leu-Ser-Pro-Val-Ile-Pro-Leu-Leu-His-Leu-Gly-OH
Long-term Storage Conditions
BMAP-27 antimicrobial peptide is freely soluble in H2O
References
1. Cheng K. et al.,mBio 7, 01418-16 (2016)
2. Skerlavaj B. et al., J Biol Chem 271(45), 28375-81(1996)
3. Pompilio A.et al., Peptides 32(9) 1807-1814 (2011)

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