Bradykinin, des-pro(3)-

Bradykinin, des-pro(3)- incorporates a targeted modification that alters structural flexibility and binding preferences. Removal of proline influences turn formation and backbone geometry. Researchers examine its solvent-dependent conformations and interaction profiles. Uses include motif-function studies, structure-activity exploration, and peptide analog design.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Bradykinin, des-pro(3)-(CAS 80943-05-1)

CAT No: R2671

CAS No:80943-05-1

Synonyms/Alias:Arg-pro-gly-phe-ser-pro-phe-arg;80943-05-1;3-De-pro-bradykinin;Bradykinin, des-pro(3)-;Bradykinin, des-proline(3)-;Bradykinin, 3-de-L-proline-;[Des-Pro2]-Bradykinin;(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid;HY-P2828;CS-0143033;H-L-Arg-L-Pro-Gly-L-Phe-L-Ser-L-Pro-L-Phe-L-Arg-OH;(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{[(2S)-1-[(2S)-2-AMINO-5-CARBAMIMIDAMIDOPENTANOYL]PYRROLIDIN-2-YL]FORMAMIDO}ACETAMIDO)-3-PHENYLPROPANAMIDO]-3-HYDROXYPROPANOYL]PYRROLIDIN-2-YL]FORMAMIDO}-3-PHENYLPROPANAMIDO]-5-CARBAMIMIDAMIDOPENTANOIC ACID;(S)-2-((S)-2-((S)-1-((S)-2-((S)-2-(2-((S)-1-((S)-2-Amino-5-guanidinopentanoyl)pyrrolidine-2-carboxamido)acetamido)-3-phenylpropanamido)-3-hydroxypropanoyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-5-guanidinopentanoic acid;

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C45H66N14O10
M.W/Mr.
963.1
Sequence
One Letter Code:RPGFSPFR
Three Letter Code:H-Arg-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH
InChI
InChI=1S/C45H66N14O10/c46-29(15-7-19-51-44(47)48)41(66)58-21-9-17-34(58)39(64)53-25-36(61)54-31(23-27-11-3-1-4-12-27)37(62)57-33(26-60)42(67)59-22-10-18-35(59)40(65)56-32(24-28-13-5-2-6-14-28)38(63)55-30(43(68)69)16-8-20-52-45(49)50/h1-6,11-14,29-35,60H,7-10,15-26,46H2,(H,53,64)(H,54,61)(H,55,63)(H,56,65)(H,57,62)(H,68,69)(H4,47,48,51)(H4,49,50,52)/t29-,30-,31-,32-,33-,34-,35-/m0/s1
InChI Key
QFSJEDMTCFOOTJ-POFDKVPJSA-N

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