CALP3

CALP3 is a cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site. Activates phosphodiesterase in the absence of Ca2+ and inhibits Ca2+-mediated cytotoxicity and apoptosis (IC50 = 33 μM).

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CAT#	10-101-306
CAS	261969-05-5
Synonyms/Alias	Calcium-like peptide 3
Chemical Name	(2S)-6-amino-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-amino-3-methylbutanoyl]amino]hexanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]hexanoic acid
M.F/Formula	C44H68N10O9
M.W/Mr.	881.1
Sequence	One Letter Code: VKFGVGFK Three Letter Code: H-Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-OH
Target	Calcium Channel

CAT#	Product Name	Inquiry
10-101-347	MeO-Suc-Arg-Pro-Tyr-pNA	Inquiry
10-101-02	Alarelin acetate	Inquiry
10-101-87	GRF (human) Acetate	Inquiry
10-101-192	Felypressin Impurity E	Inquiry
10-101-180	Solanezumab	Inquiry

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Storage	Desiccate at -20°C
Solubility	Soluble to 1 mg/ml in water
Shipping Condition	Wet ice in continental US; may vary elsewhere
InChI	InChI=1S/C44H68N10O9/c1-27(2)37(47)42(60)51-31(19-11-13-21-45)40(58)53-33(23-29-15-7-5-8-16-29)39(57)48-26-36(56)54-38(28(3)4)43(61)49-25-35(55)50-34(24-30-17-9-6-10-18-30)41(59)52-32(44(62)63)20-12-14-22-46/h5-10,15-18,27-28,31-34,37-38H,11-14,19-26,45-47H2,1-4H3,(H,48,57)(H,49,61)(H,50,55)(H,51,60)(H,52,59)(H,53,58)(H,54,56)(H,62,63)/t31-,32-,33-,34-,37-,38-/m0/s1
InChI Key	OBMFGXCPBIYSPH-FFIZALLVSA-N
Canonical SMILES	CC(C)C(C(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NCC(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCCN)C(=O)O)N
Isomeric SMILES	CC(C)[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCCN)C(=O)O)N