Z-VDVAD-FMK is a synthetic peptide that irreversibly inhibits the activity of caspase-2. It attenuates oxyhemoglobin-induced cleavage of PARP and apoptosis in endothelial cells. Z-VDVAD-FMK can be used for both in vitro and in vivo studies.
CAT No: R1111
CAS No:210344-95-9
Synonyms/Alias:Z-DEVD-FMK;210344-95-9;Caspase-3 Inhibitor;C30H41FN4O12;L-Valinamide, N-[(phenylmethoxy)carbonyl]-L-alpha-aspartyl-L-alpha-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, 1,2-dimethyl ester;benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone;methyl (4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-[[(2S)-4-methoxy-4-oxo-2-(phenylmethoxycarbonylamino)butanoyl]amino]-5-oxopentanoate;Z-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone;Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone;Z-Asp(O-Me)-Glu(O-Me)-Val-Asp(O-Me) fluoromethyl ketone;N-benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone;methyl (5S,8S,11S,14S)-14-(2-fluoroacetyl)-11-isopropyl-5-(2-methoxy-2-oxoethyl)-8-(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate;MFCD23380217;Z-DEVD-fluoromethylketone;Z-DEVD-fluoromethyl ketone;specific inhibitor of caspase-3;CHEMBL3963349;SCHEMBL18328791;DTXSID00879990;CHEBI:138013;BDBM228619;EX-A1761;HB1282;US9345789, Z-DEVD-FMK;AKOS024456968;CS-3454;AC-31504;BP-23680;BS-16593;DA-68816;FA111066;HY-12466;D71045;Z-Asp(OCH3)-Glu(OCH3)-Val-Asp(OCH3)-CH2F;Q60998625;benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone;N-benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethyl-ketone;Z-Asp(O-Me)-Glu(O-Me)-Val-Asp(O-Me) fluoromethyl ketone, >=90% (HPLC);(5S,8S,11S,14S)-methyl 14-(2-fluoroacetyl)-11-isopropyl-5-(2-methoxy-2-oxoethyl)-8-(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate;METHYL (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-{[(BENZYLOXY)CARBONYL]AMINO}-4-METHOXY-4-OXOBUTANAMIDO]-5-METHOXY-5-OXOPENTANAMIDO]-3-METHYLBUTANAMIDO]-5-FLUORO-4-OXOPENTANOATE;methyl (4S)-5-{[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]amino}-4-{[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-methoxy-4-oxobutanoyl]amino}-5-oxopentanoate;methyl (5S,8S,11S,14S)-14-(fluoroacetyl)-11-isopropyl-5-(2-methoxy-2-oxoethyl)-8-(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate;N-[(phenylmethoxy)carbonyl]-L-alpha-aspartyl-L-alpha-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-valinamide, 1,2-dimethyl ester;
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