An internally quenched fluorogenic substrate (Ab/Em =328/393 nm) for cathepsins D and E and not for B, H or L, obtained from the hepatopancreas (liver) of the Japanese common squid (Todarodes pacificus). The cleavage occurs at the Phe-Phe amide bond resulting in enhanced fluorescence and is used in screening cathepsin D and E inhibitors and for determining cathepsin D and E activity in tissue cell extracts.
CAT No: F15001
1. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
2. Myotropic activity of allatostatins in tenebrionid beetles
4. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis
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