(D-Arg0,Hyp3,D-Phe7)-Bradykinin

(D-Arg0,Hyp3,D-Phe7)-Bradykinin is a bradykinin fragment with modifications at positions 0, 3, and 7 that improve receptor-binding efficiency and metabolic stability. The hydroxyproline and D-phenylalanine residues influence peptide folding and activity in vasoactive pathways. Researchers use this peptide in studies of bradykinin-mediated vasodilation and its role in regulating blood pressure and tissue inflammation.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
(D-Arg0,Hyp3,D-Phe7)-Bradykinin(CAS 109333-26-8)

CAT No: B09035

CAS No:109333-26-8

Synonyms/Alias:Npc-567;109333-26-8;Npc 567;Arg-3-hyp-7-phe-bradykinin;(D-ARG0,HYP3,D-PHE7)-BRADYKININ;UNII-DV64B0PLEH;Bradykinin, arg-hyp(3)-phe(7)-;Bradykinin, arg(0)-hyp(3)-phe(7)-;CHEBI:73294;arg(0)-hyp(3)-phe(7)-bradykinin;DV64B0PLEH;Bradykinin, arginyl-hydroxyprolyl(3)-phenylalanine(7)-;[D-Arg(0),Hyp(3),D-Phe(7)]bradykinin;CHEMBL446325;D-Arg-Arg-Pro-Hyp-Gly-Phe-Ser-D-Phe-Phe-Arg;[D-Arg0,Hyp3,D-Phe7]bradykinin;BIM 31006;BIM-31006;Bradykinin, N2-D-arginyl-3-(trans-4-hydroxy-L-proline)-7-D-phenylalanine-;D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-seryl-D-phenylalanyl-L-phenylalanyl-L-arginine;(D-Arg0,Hyp3,D-Phe7)bradykinin;BRADYKININ, N2-D-ARGINYL-3-((4R)-4-HYDROXY-L-PROLINE)-7-D-PHENYLALANINE-;(D-Arg(0),Hyp(3),D-Phe(7))bradykinin;GTPL676;RBIXVHPHNGXTCI-QJTYZATASA-N;HY-P2118;BDBM50435301;AKOS040744757;DA-48720;FA109821;CS-0108808;Q27088026;(D-Arg0,Hyp3,D-Phe7)-Bradykinin trifluoroacetate salt;(D-Arg0, Hyp 3,D-Phe7)-Bradykinin trifluoroacetate salt;H-D-Arg-Arg-Pro-Hyp-Gly-Phe-Ser-D-Phe-Phe-Arg-OH; H-(dR)RP(hyP)GFS(dF)FR-OH;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C60H87N19O13
M.W/Mr.
1282.5
Sequence
One Letter Code:RRPXGFSFFR
Three Letter Code:H-D-Arg-Arg-Pro-Hyp-Gly-Phe-Ser-D-Phe-Phe-Arg-OH
InChI
InChI=1S/C60H87N19O13/c61-39(20-10-24-68-58(62)63)49(83)73-40(21-11-25-69-59(64)65)55(89)78-27-13-23-46(78)56(90)79-33-38(81)31-47(79)54(88)71-32-48(82)72-42(28-35-14-4-1-5-15-35)50(84)77-45(34-80)53(87)76-44(30-37-18-8-3-9-19-37)52(86)75-43(29-36-16-6-2-7-17-36)51(85)74-41(57(91)92)22-12-26-70-60(66)67/h1-9,14-19,38-47,80-81H,10-13,20-34,61H2,(H,71,88)(H,72,82)(H,73,83)(H,74,85)(H,75,86)(H,76,87)(H,77,84)(H,91,92)(H4,62,63,68)(H4,64,65,69)(H4,66,67,70)/t38-,39-,40+,41+,42+,43+,44-,45+,46+,47+/m1/s1
InChI Key
RBIXVHPHNGXTCI-QJTYZATASA-N

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