(D-Phe12,Nle21·38,alpha-Me-Leu37)-CRF (12-41) (human, rat) incorporates multiple substitutions that reshape hydrophobic surfaces and stereochemical preferences. The fragment enables detailed exploration of CRF-related receptor engagement and structural dynamics. Its modified sequence enhances stability during biophysical analysis. Researchers employ it in mapping structure-activity relationships and regulatory peptide modeling.
CAT No: C29020
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