(D-Thr2)-Leu-Enkephalin-Thr is an enkephalin analog that includes a D-threonine substitution at position 2, enhancing its binding affinity to opioid receptors. This modification makes the peptide more resistant to enzymatic degradation, making it suitable for studies on pain modulation and neuropeptide signaling. It is commonly used in research exploring the role of opioid peptides in analgesia and neuromodulation.
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