DADLE

Name: DADLE
Brand: Creative Peptides
SKU: R1886
Availability: MadeToOrder

DADLE is a prototypical δ-opioid receptor agonist that displays activity at the μ-opioid receptor and antinociceptive activity in vivo.

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CAT No: R1886

CAS No: 63631-40-3

Synonyms/Alias: DADLE;63631-40-3;H-TYR-D-ALA-GLY-PHE-D-LEU-OH;BW-180C;[D-Ala2, D-Leu5]-enkephalin;DADL;Enkephalin-leu,ala(2);2-Alanyl-leucine enkephalin;Leucine enkephalin-2-alanine;(D-Ala2,D-Leu5)-Enkephalin;5-Leucine-2-alanine enkephalin;ENKEPHALIN, LEUCINE-2-ALANINE;(D-Ala2,D-Leu5)enkephalin;H-Tyr-D-Ala-Gly-Phe-D-Leu;(2R)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid;CQK2YXW6EZ;Tyr-D-Ala-Gly-Phe-D-Leu;CHEMBL340032;D-Leucine, N-(N-(N-(N-L-tyrosyl-D-alanyl)glycyl)-L-phenylalanyl)-;L-Tyrosyl-D-alanylglycyl-L-phenylalanyl-D-leucine;[D-Ala2-D-Leu5]enkephalin;(D-Ala2, D-Leu5)-Enkephalin;(D-ALA2-D-LEU5)ENKEPHALIN;(2R,5S,11R,14S)-14-Amino-5-benzyl-15-(4-hydroxyphenyl)-2-isobutyl-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecan-1-oic acid;Leu Enkephalin 2 Ala;Leu-Enkephalin-2-Ala;2 Alanyl Leucine Enkephalin;Leucine Enkephalin 2 Alanine;Leucine-2-Alanine Enkephalin;Enkephalin, 2-Alanyl-Leucine;Enkephalin, Leucine 2 Alanine;Enkephalin-2-Alanine, Leucine;5 Leucine 2 Alanine Enkephalin;Enkephalin, 5-Leucine-2-Alanine;D-Ala(2)-D-Leu(5)-Enkephalin;(2R)-2-(((2S)-2-((2-(((2R)-2-(((2S)-2-amino-3-(4-hydroxyphenyl)propanoyl)amino)propanoyl)amino)acetyl)amino)-3-phenylpropanoyl)amino)-4-methylpentanoic acid;DADLE-OH;UNII-HB4QD9GL6F;GTPL1607;SCHEMBL11124725;BDBM21025;AKOS024457800;DB08856;ENKEPHALIN-(2-D-ALA, 5-D-LEU);FA108791;TS-10506;HY-105343;CS-0025794;NS00071158;G77857;Q424905;TYROSYL-D-ALANYLGLYCYLPHENYLALANYL-D-LEUCINE;D-Leucine, L-tyrosyl-D-alanylglycyl-L-phenylalanyl-;H-Tyr-D-Ala-Gly-Phe-D-Leu-OH; H-Y(dA)GF(dL)-OH;(2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid;

Chemical Name: (2R)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C29H39N5O7
M.W/Mr.	569.6
Sequence	One Letter Code:YAGFL Three Letter Code:H-Tyr-D-Ala-Gly-Phe-D-Leu-OH
Purity	> 95%

Long-term Storage Conditions	Soluble to 1 mg/ml in water
Shipping Condition	RT, or blue ice upon request.
InChI	InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22+,23+,24-/m1/s1
InChI Key	ZHUJMSMQIPIPTF-IBURTVSXSA-N
Canonical SMILES	CC(C)CC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)C(C)NC(=O)C(CC2=CC=C(C=C2)O)N
Isomeric SMILES	C[C@H](C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC(C)C)C(=O)O)NC(=O)[C@H](CC2=CC=C(C=C2)O)N

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4. A possible role of tachykinin-related peptide on an immune system activity of mealworm beetle, Tenebrio molitor L

5. Uncarboxylated osteocalcin decreases insulin-stimulated glucose uptake without affecting insulin signaling and regulators of mitochondrial biogenesis in myotubes

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