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Decapeptide-12

Decapeptide-12 is a synthetic oligopeptide composed of ten amino acids, designed for use in cosmetic formulations targeting uneven skin tone and hyperpigmentation concerns. By modulating the appearance of skin discoloration, Decapeptide-12 supports the development of products aimed at promoting a more uniform complexion. Its compatibility with various formulation types and stability under typical cosmetic conditions make it suitable for inclusion in serums, creams, and other topical applications.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Decapeptide-12(CAS 137665-91-9)

CAT No: HB00126

CAS No:137665-91-9

Synonyms/Alias:Decapeptide-12;137665-91-9;DA-52389;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C65H90N18O17
M.W/Mr.
1395.5
Sequence
One Letter Code:YRSRKYSSWY
Three Letter Code:H-DL-Tyr-DL-Arg-DL-Ser-DL-Arg-DL-Lys-DL-Tyr-DL-Ser-DL-Ser-DL-Trp-DL-Tyr-OH

Mechanism of Action (MOA)

Decapeptide-12 is a synthetic oligopeptide composed of ten amino acids. It interacts with melanocyte cellular pathways by modulating the activity of tyrosinase, an enzyme involved in melanin biosynthesis. Through this biochemical interaction, Decapeptide-12 influences the signaling processes that regulate melanin production at the cellular level. This peptide is designed for topical cosmetic formulations targeting the appearance of skin tone and uniformity, aligning with established cosmetic mechanisms.

Decapeptide-12 can be incorporated into various cosmetic formulations to support targeted skincare product development.

- Suitable for inclusion in facial serums and creams
- Can be formulated into under-eye treatments
- Compatible with emulsions and gel-based systems
- May be added to brightening masks and spot correctors
- Appropriate for use in daily skincare routines
- Stable in pH ranges typical for cosmetic products

Shipping Condition
Room temperature in continental US; may vary elsewhere.
InChI
InChI=1S/C65H90N18O17/c66-24-4-3-9-45(76-55(91)47(11-6-26-73-65(70)71)77-60(96)51(32-84)81-57(93)46(10-5-25-72-64(68)69)75-54(90)43(67)27-35-12-18-39(87)19-13-35)56(92)78-48(28-36-14-20-40(88)21-15-36)58(94)82-53(34-86)62(98)83-52(33-85)61(97)79-49(30-38-31-74-44-8-2-1-7-42(38)44)59(95)80-50(63(99)100)29-37-16-22-41(89)23-17-37/h1-2,7-8,12-23,31,43,45-53,74,84-89H,3-6,9-11,24-30,32-34,66-67H2,(H,75,90)(H,76,91)(H,77,96)(H,78,92)(H,79,97)(H,80,95)(H,81,93)(H,82,94)(H,83,98)(H,99,100)(H4,68,69,72)(H4,70,71,73)
InChI Key
OYVFAMLECFSFEI-UHFFFAOYSA-N

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