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Defensin HNP-1 (Human)

Human defensin-1 (HNP-1) is a peptide possessing both broad antimicrobial (both Gram-positive and Gram-negative bacteria) and cytotoxic activities. HNP-1 reduces adenoviral infection by more than 95%.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Defensin HNP-1 (Human)(CAS 99287-08-8)

CAT No: 10-101-279

CAS No:99287-08-8

Synonyms/Alias:Defensin HNP-1 human >=80% (HPLC);99287-08-8;136661-76-2(free acid basis);Defensin HNP-3 (human) trifluoroacetate salt;FD110457;FD110458;Defensin HNP-1 (human) trifluoroacetate salt;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C150H222N44O38S6
M.W/Mr.
3442
Sequence
One Letter Code:ACYCRXPACXAGERRYGXCXYQGRLWAFCC
Three Letter Code:H-DL-Ala-DL-Cys(1)-DL-Tyr-DL-Cys(2)-DL-Arg-DL-xiIle-DL-Pro-DL-Ala-DL-Cys(3)-DL-xiIle-DL-Ala-Gly-DL-Glu-DL-Arg-DL-Arg-DL-Tyr-Gly-DL-xiThr-DL-Cys(2)-DL-xiIle-DL-Tyr-DL-Gln-Gly-DL-Arg-DL-Leu-DL-Trp-DL-Ala-DL-Phe-DL-Cys(3)-DL-Cys(1)-OH
Purity
>95%
Shipping Condition
Shipped at room temperature
InChI
InChI=1S/C150H222N44O38S6/c1-14-74(6)116-142(227)171-78(10)121(206)166-64-112(200)173-97(49-51-115(203)204)129(214)175-93(32-23-53-162-148(155)156)127(212)174-94(33-24-54-163-149(157)158)128(213)180-99(59-83-36-42-87(196)43-37-83)125(210)168-66-114(202)190-119(81(13)195)144(229)188-108-71-236-233-68-105-136(221)176-95(34-25-55-164-150(159)160)130(215)193-118(76(8)16-3)145(230)194-56-26-35-110(194)141(226)170-80(12)123(208)185-107(139(224)191-116)70-235-234-69-106(138(223)189-109(146(231)232)72-238-237-67-104(184-120(205)77(9)151)137(222)181-101(135(220)186-105)60-84-38-44-88(197)45-39-84)187-134(219)100(58-82-27-18-17-19-28-82)178-122(207)79(11)169-131(216)103(62-86-63-165-91-30-21-20-29-90(86)91)182-132(217)98(57-73(4)5)179-126(211)92(31-22-52-161-147(153)154)172-113(201)65-167-124(209)96(48-50-111(152)199)177-133(218)102(61-85-40-46-89(198)47-41-85)183-143(228)117(75(7)15-2)192-140(108)225/h17-21,27-30,36-47,63,73-81,92-110,116-119,165,195-198H,14-16,22-26,31-35,48-62,64-72,151H2,1-13H3,(H2,152,199)(H,166,206)(H,167,209)(H,168,210)(H,169,216)(H,170,226)(H,171,227)(H,172,201)(H,173,200)(H,174,212)(H,175,214)(H,176,221)(H,177,218)(H,178,207)(H,179,211)(H,180,213)(H,181,222)(H,182,217)(H,183,228)(H,184,205)(H,185,208)(H,186,220)(H,187,219)(H,188,229)(H,189,223)(H,190,202)(H,191,224)(H,192,225)(H,193,215)(H,203,204)(H,231,232)(H4,153,154,161)(H4,155,156,162)(H4,157,158,163)(H4,159,160,164)
InChI Key
KRJOFJHOZZPBKI-UHFFFAOYSA-N

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