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Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2

Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2 contains a dinitrophenyl group that enhances chromophoric detection and influences hydrophobic packing. The sequence combines aromatic and basic residues useful for studying peptide-protein interactions. Researchers examine its conformational preferences and solvent-dependent folding. Its tailored design aids spectrophotometric kinetic analyses.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: 10-101-254

CAS No:121282-17-5

Synonyms/Alias:MMP Substrate, Fluorogenic

Chemical Name:N-(2,4-Dinitrophenyl)-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg amide

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C45H64N14O11
M.W/Mr.
977.08
Sequence
One Letter Code: Dnp-PLGLWAR
Three Letter Code: Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2 (Dnp=2,4-dinitrophenyl)
Purity
≥98% (HPLC)
Shipping Condition
Shipped with blue ice
InChI
InChI=1S/C45H64N14O11/c1-24(2)18-34(56-41(63)32-12-8-16-48-32)40(62)51-23-38(60)53-35(19-25(3)4)44(66)57-36(20-27-22-50-30-11-7-6-10-29(27)30)43(65)52-26(5)39(61)55-33(13-9-17-49-45(46)47)42(64)54-31-15-14-28(58(67)68)21-37(31)59(69)70/h6-7,10-11,14-15,21-22,24-26,32-36,48,50H,8-9,12-13,16-20,23H2,1-5H3,(H,51,62)(H,52,65)(H,53,60)(H,54,64)(H,55,61)(H,56,63)(H,57,66)(H4,46,47,49)/t26-,32-,33-,34-,35-,36-/m0/s1
InChI Key
ZULOKZMJGSWWKA-PGVZYDAFSA-N
Canonical SMILES
CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-]

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