DPC-AG1166-00 (L-Isomer) is a stereochemically defined, L-configured amino acid derivative belonging to the amino acid building-block class used in peptide and chemical biology workflows. The molecule contains both amino and carboxyl functional groups and bears a side chain characteristic of its specific amino acid scaffold, with the L-isomer designation indicating a defined stereochemical relationship at the alpha carbon that can influence coupling behavior and conformational preferences. In synthesis and labeling contexts, it is employed as a defined amino acid component for constructing modified peptide structures or for preparing downstream amino acid derivatives where stereochemical control and side-chain functionality are required for subsequent derivatization, conjugation, or analytical characterization.
CAT No: CP26942
CAS No:277316-24-2
Synonyms/Alias:[2,6-Dimethyl-4-(3-[2-(Z-amino)-ethylcarbamoyl]-propoxy)-benzenesulfonyl]-Dap(Boc)-OMe;SCHEMBL8313513;ZINC150364212;[2,6-DIMETHYL-4-(3-[2--BENZENESULFONYL]-D-DAP-OME;277316-24-2
DPC-AG1166-00 (L-Isomer) is an L-configured amino acid building block supplied for research and development workflows where stereochemical fidelity is critical. As an amino acid reagent, it is typically selected for assembly into peptide-related intermediates or for use in chemical biology and analytical method development that benefits from a defined chiral center. Its established use in downstream coupling and characterization workflows makes it a practical choice for teams building stereochemically defined compounds rather than relying on racemic mixtures.
1. Peptide Building Block Use
DPC-AG1166-00 (L-Isomer) is commonly used as a stereodefined amino acid building block in custom peptide synthesis and peptide intermediate preparation, where the L-configuration is required to match a target sequence or to control the stereochemical outcome of subsequent coupling steps. Research groups developing peptide libraries, segment-based peptide assembly, or specialized peptide analogs often choose an L-isomer to avoid sequence ambiguity and to improve interpretability in downstream characterization such as chromatographic profiling and mass-based confirmation. In these workflows, the reagent is handled as a defined chiral component that integrates into standard peptide synthesis and purification pipelines used by peptide chemistry laboratories and contract peptide manufacturing teams.
2. Pharmaceutical Intermediate Development
DPC-AG1166-00 (L-Isomer) finds frequent application in pharmaceutical intermediate development and specialty chemical manufacturing where amino acid-derived fragments are required as stereochemically consistent inputs. Medicinal chemistry groups use such chiral amino acid building blocks to construct well-defined intermediates for structure-activity relationship studies, enabling reliable comparison across analog series without introducing stereochemical variability. The L-isomer form is particularly valuable when the downstream chemistry depends on maintaining a specific stereochemical configuration through multi-step synthesis, and when intermediates must be characterized and documented as single-chirality materials for internal project traceability.
3. Analytical Standard And Method Workflows
DPC-AG1166-00 (L-Isomer) is also used to support analytical standard preparation and method development in laboratories that require chiral, amino-acid-derived reference material. Analytical chemists use defined L-isomer reagents to validate sample identity, assess derivatization performance, and support method robustness in workflows such as amino acid profiling, chiral separation development, and LC-MS or related confirmatory analyses. Because stereochemistry can strongly influence retention behavior and derivatized product profiles, supplying an L-specific reagent helps ensure that calibration and verification steps reflect the stereochemical form expected in the experimental samples.
4. Chiral Synthesis Reference Material
DPC-AG1166-00 (L-Isomer) serves as a practical chiral reference input for chemical synthesis development where stereochemical integrity must be monitored across reaction sequences. In R&D settings, chemists use the L-isomer to benchmark chiral outcomes, support process development documentation, and provide a consistent comparator for evaluating stereochemical purity during intermediate handling. This application is especially relevant for teams working on stereochemically defined amino acid derivatives and peptide-related fragments, where consistent chiral starting material reduces ambiguity in interpretation and supports reproducible downstream processing.
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