Registration of APIs CMC information required for an IND
IND and NDA support Drug master files (DMF) filing
Synonyms/Alias | Enhanced Green Fluorescent Protein (EGFP) (200-208);323198-39-6;AKOS040758044;DA-73110;MS-31869;PD196344;(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-4-methylpentanoic acid; |
M.F/Formula | C45H70N12O15 |
M.W/Mr. | 1019.1 |
Sequence | One Letter Code:HYLSTQSAL Three Letter Code:H-His-Tyr-Leu-Ser-Thr-Gln-Ser-Ala-Leu-OH |
InChI | InChI=1S/C45H70N12O15/c1-21(2)13-30(53-41(67)31(15-25-7-9-27(61)10-8-25)52-38(64)28(46)16-26-17-48-20-49-26)40(66)56-34(19-59)43(69)57-36(24(6)60)44(70)51-29(11-12-35(47)62)39(65)55-33(18-58)42(68)50-23(5)37(63)54-32(45(71)72)14-22(3)4/h7-10,17,20-24,28-34,36,58-61H,11-16,18-19,46H2,1-6H3,(H2,47,62)(H,48,49)(H,50,68)(H,51,70)(H,52,64)(H,53,67)(H,54,63)(H,55,65)(H,56,66)(H,57,69)(H,71,72)/t23-,24+,28-,29-,30-,31-,32-,33-,34-,36-/m0/s1 |
InChI Key | HPQYOZPSZAHWMK-PMGPJPFJSA-N |
3. Cationic cell-penetrating peptides are potent furin inhibitors
4. Implications of ligand-receptor binding kinetics on GLP-1R signalling
5. Emerging applications of nanotechnology for diagnosis and therapy of disease: a review
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