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Gastrin I (human)

Gastrin-1, human is the endogenous peptide produced in the stomach, and increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Gastrin I (human)(CAS 10047-33-3)

CAT No: HB00095

CAS No:10047-33-3

Synonyms/Alias:Gastrin I human;Gastrin-17;Gastrin I (human);Little gastrin I;10047-33-3;Gastrin 17;Gastrin heptadecapeptide;Heptadecapeptide gastrin;60748-06-3;Little gastrin;G 17;Gastrin centn, human;CHEMBL4451154;Shg17NS;C97H124N20O31S;GastrinIHuman;Gastrin-1;Gastrin-I (human);MFCD00076500;desulfated gastrin-17;XGPWLEEEEEAYGWMDF;18-34-Gastrin, 18-(5-oxo-L-proline)-;GTPL8408;CHEBI:75441;DTXSID601028770;BDBM50517370;HB3575;Gastrin I human, >=95% (HPLC);AKOS024457376;AS-56740;DA-63707;(X = Glp, Phe-17 = C-terminal amide);A11815;Q6652696;Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2;5-oxo-L-prolylglycyl-L-prolyl-L-tryptophyl-L-leucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-tyrosylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide;

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cGMP Peptide
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M.F/Formula
C97H124N20O31S
M.W/Mr.
2098.2
Sequence
One Letter Code:XGPWLEEEEEAYGWMDF
Three Letter Code:H-Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
Biological Activity
Endogenous peptide produced in the stomach that acts as a selective CCK2 receptor agonist. Stimulates gastric acid secretion. Also used in the culture of stomach organoids.
Long-term Storage Conditions
Soluble to 1 mg/ml in 1% Ammonia with sonication
Shipping Condition
Room temperature in continental US; may vary elsewhere.
InChI
InChI=1S/C97H124N20O31S/c1-49(2)39-68(114-95(146)71(43-54-46-100-59-18-11-9-16-57(54)59)116-97(148)73-19-12-37-117(73)76(121)48-102-85(136)60-24-30-74(119)104-60)93(144)110-65(29-35-81(130)131)91(142)109-64(28-34-80(128)129)90(141)108-63(27-33-79(126)127)89(140)107-62(26-32-78(124)125)88(139)106-61(25-31-77(122)123)87(138)103-50(3)84(135)113-69(41-52-20-22-55(118)23-21-52)86(137)101-47-75(120)105-70(42-53-45-99-58-17-10-8-15-56(53)58)94(145)111-66(36-38-149-4)92(143)115-72(44-82(132)133)96(147)112-67(83(98)134)40-51-13-6-5-7-14-51/h5-11,13-18,20-23,45-46,49-50,60-73,99-100,118H,12,19,24-44,47-48H2,1-4H3,(H2,98,134)(H,101,137)(H,102,136)(H,103,138)(H,104,119)(H,105,120)(H,106,139)(H,107,140)(H,108,141)(H,109,142)(H,110,144)(H,111,145)(H,112,147)(H,113,135)(H,114,146)(H,115,143)(H,116,148)(H,122,123)(H,124,125)(H,126,127)(H,128,129)(H,130,131)(H,132,133)/t50-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-/m0/s1
InChI Key
GKDWRERMBNGKCZ-RNXBIMIWSA-N

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