GIP (3-42), human lacks the first two residues while preserving the core receptor-binding domain. Truncation at the N-terminus enables examination of structural contributions to activation versus binding. Researchers use this analog to map degradation products and enzymatic cleavage patterns. Its sequence supports detailed structure-activity and metabolic pathway studies.
2. TMEM16F and dynamins control expansive plasma membrane reservoirs
3. The spatiotemporal control of signalling and trafficking of the GLP-1R
4. Emerging applications of nanotechnology for diagnosis and therapy of disease: a review
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