GIP (3-42), human lacks the first two residues while preserving the core receptor-binding domain. Truncation at the N-terminus enables examination of structural contributions to activation versus binding. Researchers use this analog to map degradation products and enzymatic cleavage patterns. Its sequence supports detailed structure-activity and metabolic pathway studies.
3. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
4. Emu oil in combination with other active ingredients for treating skin imperfections
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