Glutamate Receptor Endocytosis Inhibitor, GluR23Y

Name: Glutamate Receptor Endocytosis Inhibitor, GluR23Y
Brand: Creative Peptides
Rating: 5 (1 reviews)

This GluR23Y peptide was used in ELISA cell-surface assay for the insulin-stimulated endocytosis of native AMPA receptors in cultured hippocampal neurons. GluR23Y prevented any insulin-induced reduction. The blockade of insulin action was observed when the GluR23Y peptide was delivered into neurons by fusing it to the membrane transduction domain of HIV-1.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: X21193

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.W/Mr.

1092.2

Sequence

One Letter Code: YKEGYNVYG
Three Letter Code: H-Tyr-Lys-Glu-Gly-Tyr-Asn-Val-Tyr-Gly-OH

References

1. Ahmadian, G. et al. EMBO J. 23, 1040 (2004),
2. Wang, D. et al. J. Biol. Chem. 279, 41267 (2004).

1. High fat diet and GLP-1 drugs induce pancreatic injury in mice

2. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

3. Quantitative Analysis of Ligands Effects on Bioefficacy of Nanoemulsion encapsulating Depigmenting Active

4. Spatiotemporal delivery of nanoformulated liraglutide for cardiac regeneration after myocardial infarction

5. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment

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