H-Gly-Arg-AMC

H-Gly-Arg-AMC links a minimal dipeptide recognition element to an AMC fluorophore, forming a sensitive substrate for trypsin-like proteases. The arginine residue defines cleavage specificity, while glycine provides flexibility. Researchers quantify fluorescence increase to monitor catalytic turnover. Applications include high-throughput screening, kinetic analysis, and protease-mechanism research.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
H-Gly-Arg-AMC(CAS 65147-19-5)

CAT No: R2570

CAS No:65147-19-5

Synonyms/Alias:H-Gly-Arg-AMC;Gly-Arg-AMC;65147-19-5;(2S)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)-N-(4-methyl-2-oxochromen-7-yl)pentanamide;Gly-Arg-7-Amino-4-Methylcoumarin;glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide, hydrochloride;70274-78-1;(S)-2-(2-Aminoacetamido)-5-guanidino-N-(4-methyl-2-oxo-2H-chromen-7-yl)pentanamide;H-Gly-Arg-AMC hydrochloride salt;Gly-Arg-AMC (hydrochloride);CHEMBL65584;SCHEMBL7574189;HY-P4342;FG110503;CS-0653705;(2S)-2-[(2-aminoacetyl)amino]-5-guanidino-N-(4-methyl-2-oxo-chromen-7-yl)pentanamide;

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C18H24N6O4
M.W/Mr.
388.4
Sequence
One Letter Code:GR
Three Letter Code:H-Gly-Arg-AMC
InChI
InChI=1S/C18H24N6O4/c1-10-7-16(26)28-14-8-11(4-5-12(10)14)23-17(27)13(24-15(25)9-19)3-2-6-22-18(20)21/h4-5,7-8,13H,2-3,6,9,19H2,1H3,(H,23,27)(H,24,25)(H4,20,21,22)/t13-/m0/s1
InChI Key
JNTASUHAFOHMQK-ZDUSSCGKSA-N

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