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H-Tyr-Phe-Met-Arg-Phe-NH2

H-Tyr-Phe-Met-Arg-Phe-NH2 is a pentapeptide rich in aromatic and basic residues, forming diverse secondary-structure tendencies. The amidated C-terminus improves backbone stability and reduces terminal flexibility. Researchers use it to probe hydrophobic clustering, ligand recognition, and enzymatic susceptibility. Its defined motif supports biophysical and structural studies.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
H-Tyr-Phe-Met-Arg-Phe-NH2(CAS 99414-63-8)

CAT No: 10-101-308

CAS No:99414-63-8

Synonyms/Alias:H-TYR-PHE-MET-ARG-PHE-NH2;99414-63-8;Tyr-Phe-Met-Arg-Phe-NH2;(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide;(S)-N-((S)-1-Amino-1-oxo-3-phenylPropan-2-yl)-2-((S)-2-((S)-2-((S)-2-amino-3-(4-hydroxyphenyl)Propanamido)-3-phenylPropanamido)-4-(methylthio)butanamido)-5-guanidinopentanamide;

Chemical Name:(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide

Custom Peptide Synthesis
cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C38H51N9O6S
M.W/Mr.
761.9
Sequence
One Letter Code:YFMRF
Three Letter Code:H-Tyr-Phe-Met-Arg-Phe-NH2
Appearance
White or off-white lyophilized powder
Purity
0.97
Shipping Condition
+20°C (International: -20°C)
InChI
InChI=1S/C38H51N9O6S/c1-54-20-18-30(36(52)44-29(13-8-19-43-38(41)42)35(51)46-31(33(40)49)22-24-9-4-2-5-10-24)45-37(53)32(23-25-11-6-3-7-12-25)47-34(50)28(39)21-26-14-16-27(48)17-15-26/h2-7,9-12,14-17,28-32,48H,8,13,18-23,39H2,1H3,(H2,40,49)(H,44,52)(H,45,53)(H,46,51)(H,47,50)(H4,41,42,43)/t28-,29-,30-,31-,32-/m0/s1
InChI Key
XIGYVHAASVGIGA-XDIGFQIYSA-N
Canonical SMILES
CSCCC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC3=CC=C(C=C3)O)N
Isomeric SMILES
CSCC[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC3=CC=C(C=C3)O)N

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