Hyaluronan-Binding Peptide, biotin labeled

This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.

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M.W/Mr.2012.4
SequenceOne Letter Code: GAHWQFNALTVRGGGS-K(Biotin)
Three Letter Code: H-Gly-Ala-His-Trp-Gln-Phe-Asn-Ala-Leu-Thr-Val-Arg-Gly-Gly-Gly-Ser-Lys(Biotin)-OH
References1. Mahaffey, C. and ME Mummert. J Immunol 179, 8191 (2007);
2. Mummert, M. et al. J Exp Med 192, 769 (2000).
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