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KR-12 (human)

KR-12 (human) is a truncated antimicrobial peptide fragment derived from cathelicidin LL-37. Its cationic and amphipathic properties support studies on membrane disruption and helix formation. Researchers apply it to explore sequence-dependent antimicrobial mechanisms. The peptide aids design of compact bioactive analogs.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
KR-12 (human)(CAS 1218951-51-9)

CAT No: L07006

CAS No:1218951-51-9

Synonyms/Alias:KR-12 (human);1218951-51-9;CHEMBL4174313;HY-P10257;CS-1050292;

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C71H127N25O15
M.W/Mr.
1570.9
Sequence
One Letter Code:KRIVQRIKDFLR
Three Letter Code:H-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-NH2
InChI
InChI=1S/C71H127N25O15/c1-9-40(7)55(67(110)89-45(24-15-17-31-73)59(102)93-51(37-53(98)99)65(108)92-50(36-42-21-12-11-13-22-42)64(107)91-49(35-38(3)4)63(106)86-44(57(76)100)25-18-32-83-69(77)78)95-62(105)47(27-20-34-85-71(81)82)88-60(103)48(28-29-52(75)97)90-66(109)54(39(5)6)94-68(111)56(41(8)10-2)96-61(104)46(26-19-33-84-70(79)80)87-58(101)43(74)23-14-16-30-72/h11-13,21-22,38-41,43-51,54-56H,9-10,14-20,23-37,72-74H2,1-8H3,(H2,75,97)(H2,76,100)(H,86,106)(H,87,101)(H,88,103)(H,89,110)(H,90,109)(H,91,107)(H,92,108)(H,93,102)(H,94,111)(H,95,105)(H,96,104)(H,98,99)(H4,77,78,83)(H4,79,80,84)(H4,81,82,85)/t40-,41-,43-,44-,45-,46-,47-,48-,49-,50-,51-,54-,55-,56-/m0/s1
InChI Key
DWPIYOBYHJUPAG-ZFXZXRHDSA-N

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