L-METHIONINE SULFONE (1-13C) is an isotopically labeled, proteinogenic amino acid derivative in which the side-chain thioether of L-methionine is oxidized to a sulfone and one carbon atom is labeled with 13C. The molecule contains an amino group and a carboxyl group on the α-carbon, while the sulfone-bearing side chain provides a strongly electron-withdrawing, polar functionality compared with the parent thioether and retains the stereochemistry associated with the L-designation. As a labeled methionine analog, it is used in chemical biology and analytical studies such as isotopic tracing, mass spectrometric method development, and incorporation into peptide or amino-acid derivative syntheses where a defined oxidation state and 13C labeling at the specified position are required.
CAT No: L-Iso-0447
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