Larazotide is an octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease.
CAT# | R1967 |
Chemical Structure | |
CAS | 258818-34-7 |
Synonyms/Alias | Larazotide; AT-2347; AT 2347; AT2347; glycyl-glycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolyl-glycine |
Chemical Name | 2-[[(2S)-1-[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]acetic acid |
M.F/Formula | C32H55N9O10 |
M.W/Mr. | 725.8 |
Sequence | One Letter Code: GGVLVQPG Three Letter Code: H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH |
Appearance | Solid powder |
Biological Activity | Larazotide is an octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease. |
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