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MC-VC-Pab-NH2

MC-VC-PAB-NH2 incorporates a maleimide-capable moiety, a Val-Cit protease-cleavable linker, and a para-aminobenzyl self-immolative spacer. The construct is frequently evaluated as a modular unit in conjugate and prodrug design. Researchers quantify cleavage kinetics and payload-release profiles in enzymatic systems. Applications include linker-technology optimization, targeted-delivery modeling, and protease-mechanism studies.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
MC-VC-Pab-NH2(CAS 1616727-20-8)

CAT No: R2710

CAS No:1616727-20-8

Synonyms/Alias:MC-VC-PAB-NH2;1616727-20-8;SCHEMBL15868007;{4-[(2S)-5-(carbamoylamino)-2-[(2S)-2-[6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido]-3-methylbutanamido]pentanamido]phenyl}methyl N-(2-aminoethyl)carbamate;AKOS040756930;[4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl N-(2-aminoethyl)carbamate;DA-55296;HY-136132;CS-0119676;

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M.F/Formula
C31H46N8O8
M.W/Mr.
658.7
InChI
InChI=1S/C31H46N8O8/c1-20(2)27(38-24(40)8-4-3-5-18-39-25(41)13-14-26(39)42)29(44)37-23(7-6-16-34-30(33)45)28(43)36-22-11-9-21(10-12-22)19-47-31(46)35-17-15-32/h9-14,20,23,27H,3-8,15-19,32H2,1-2H3,(H,35,46)(H,36,43)(H,37,44)(H,38,40)(H3,33,34,45)/t23-,27-/m0/s1
InChI Key
CNKMVFCYQSFWSZ-HOFKKMOUSA-N

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