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Mca-PLGL-Dpa-AR-NH2

Mca-PLGL-Dpa-AR-NH2 incorporates an Mca fluorophore and Dpa quencher flanking a protease-sensitive PLGL sequence. Cleavage separates donor and quencher, leading to fluorescence enhancement. Researchers employ the construct to quantify matrix metalloproteinase activity. Applications include real-time protease imaging in vitro, inhibitor screening, and kinetic-mechanism analysis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Mca-PLGL-Dpa-AR-NH2(CAS 1135689-33-6)

CAT No: R2547

CAS No:1135689-33-6

Synonyms/Alias:Mca-PLGL-Dpa-AR-NH2;1135689-33-6;HY-P3474;DA-55275;PD076947;CS-0611315;

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M.F/Formula
C43H66N12O11
M.W/Mr.
927.1
Sequence
One Letter Code:PLGLXAR
InChI
InChI=1S/C43H66N12O11/c1-22(2)15-29(53-42(64)32-10-8-14-55(32)35(57)17-25-18-36(58)66-33-19-26(65-6)11-12-27(25)33)39(61)49-21-34(56)51-30(16-23(3)4)40(62)54-31(20-44)41(63)50-24(5)38(60)52-28(37(45)59)9-7-13-48-43(46)47/h11-12,18-19,22-24,28-32H,7-10,13-17,20-21,44H2,1-6H3,(H2,45,59)(H,49,61)(H,50,63)(H,51,56)(H,52,60)(H,53,64)(H,54,62)(H4,46,47,48)/t24-,28-,29-,30-,31-,32-/m0/s1
InChI Key
GNGRCYXAOSUGRN-KNIQQNQGSA-N

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