MCL 0020

Name: MCL 0020
Brand: Creative Peptides
SKU: R0999
Availability: MadeToOrder

MCL 0020 is an effective and selective antagonist of peptidemimetic melanocortin MC4 receptor (IC50 =11.63 nM), exhibits anxiolytic-like activity in vivo.

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CAT No: R0999

CAS No: 475498-26-1

Synonyms/Alias: MCL 0020;475498-26-1;475498-27-2;Ac-D-2Nal-Arg-D-2Nal-NH2;SCHEMBL6552897;DTXSID801133238;AUA49826;AKOS024457630;DA-65294;TS-10499;D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-3-(2-naphthalenyl)-;(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-N-[(2R)-1-amino-3-naphthalen-2-yl-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide;(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-N-[(2R)-1-amino-3-naphthalen-2-yl-1-oxopropan-2-yl]-5-carbamimidamidopentanamide; MCL 0020;(2S)-5-carbamimidamido-N-[(1R)-1-carbamoyl-2-(naphthalen-2-yl)ethyl]-2-[(2R)-2-acetamido-3-(naphthalen-2-yl)propanamido]pentanamide;(S)-2-((R)-2-Acetamido-3-(naphthalen-2-yl)propanamido)-N-((R)-1-amino-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide;

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C34H39N7O4
M.W/Mr.	609.7
Sequence	One Letter Code:XRX Three Letter Code:Ac-D-2Nal-Arg-D-2Nal-NH2
Appearance	White lyophilised solid
Purity	>98 %
Activity	Antagonist

Shipping Condition	Wet ice in continental US; may vary elsewhere
InChI	InChI=1S/C34H39N7O4/c1-21(42)39-30(20-23-13-15-25-8-3-5-10-27(25)18-23)33(45)40-28(11-6-16-38-34(36)37)32(44)41-29(31(35)43)19-22-12-14-24-7-2-4-9-26(24)17-22/h2-5,7-10,12-15,17-18,28-30H,6,11,16,19-20H2,1H3,(H2,35,43)(H,39,42)(H,40,45)(H,41,44)(H4,36,37,38)/t28-,29+,30+/m0/s1
InChI Key	FJFLYSMWSRRMRO-FRXPANAUSA-N
Isomeric SMILES	CC(=O)N[C@H](CC1=CC2=CC=CC=C2C=C1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC3=CC4=CC=CC=C4C=C3)C(=O)N

1. Immune responses to peptides containing homocitrulline or citrulline in the DR4-transgenic mouse model of rheumatoid arthritis

2. Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation

3. Identification, Localization in the Central Nervous System and Novel Myostimulatory Effect of Allatostatins in Tenebrio molitor Beetle

4. Olfactory receptor based piezoelectric biosensors for detection of alcohols related to food safety applications

5. Zeta-potential-changing nanoparticles conjugated with cell-penetrating peptides for enhanced transfection efficiency

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