MCL 0020

Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.

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CAT#R0999
ExplanationMCL 0020 is an effective and selective antagonist of peptidemimetic melanocortin MC4 receptor (IC50 =11.63 nM), exhibits anxiolytic-like activity in vivo.
Synonyms/AliasN-Acetyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-3-(2-naphthalenyl)-L-alaninamide
M.F/FormulaC34H39N7O4
M.W/Mr.609.73
SequenceOne Letter Code: Ac-2Nal-R-2Nal
Three Letter Code: Ac-D-2Nal-Arg-D-2Nal-NH2
AppearanceWhite lyophilised solid
Purity>98 %
ActivityAntagonist
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