MEN 10376

Name: MEN 10376
Brand: Creative Peptides
SKU: R1024
Availability: MadeToOrder

Potent, highly selective NK2 neurokinin receptor antagonist.

Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

CAT No: R1024

CAS No: 135306-85-3

Synonyms/Alias: Men 10376;135306-85-3;MEN-10376;neurokinin A(4-10), Tyr(5)-Trp(6,8,9)-Lys(10)-;MEN-10,376;MFCD00144736;(3S)-3-amino-4-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid;CHEMBL507824;MEN10376;L-Lysinamide, L-alpha-aspartyl-L-tyrosyl-D-tryptophyl-L-valyl-D-tryptophyl-D-tryptophyl-;Neurokinin-2 receptor antagonist;(3S)-3-amino-4-(((2S)-1-(((2R)-1-(((2S)-1-(((2R)-1-(((2R)-1-(((2S)-1,6-diamino-1-oxohexan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)amino)-4-oxobutanoic acid;5-Tyr-6,8,9-trp-10-lys-neurokinin A (4-10);GTPL2116;HY-P1276;BDBM50259674;Neurokinin A(4-10), tyrosyl(5)-tryptophyl(6,8,9)-lysine(10)-;AKOS030623006;NCGC00167321-01;DA-48909;CS-0029214;Asp-Tyr-D-Trp-Val-D-Trp-D-Trp-Lys-NH(2);Q27084374;(Tyr5,D-Trp6.8.9,Lys-NH21?)-Neurokinin A (4-10);(Tyr5,D-Trp6?8?9,Lys-NH210)-Neurokinin A (4-10);L-Lysinamide,l-a-aspartyl-l-tyrosyl-D-tryptophyl-L-valyl-D-tryptophyl-D-tryptophyl-;(3S)-3-amino-3-{[(1S)-1-{[(1R)-1-{[(1S)-1-{[(1R)-1-{[(1R)-1-{[(1S)-5-amino-1-carbamoylpentyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}propanoic acid;(S)-3-amino-4-((S)-1-((R)-1-((S)-1-((R)-1-((R)-1-((S)-1,6-diamino-1-oxohexan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-oxobutanoic acid;

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C57H68N12O10
M.W/Mr.	1081.2
Sequence	One Letter Code:DYWVWWK Three Letter Code:H-Asp-Tyr-D-Trp-Val-D-Trp-D-Trp-Lys-NH2
Labeling Target	NK2 Receptors
Appearance	Off-white lyophilised solid
Purity	>99%
Activity	Antagonist

Long-term Storage Conditions	Soluble in Water
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage Conditions	Dry, dark and at 0 - 4 °C
Solubility	-20 °C
InChI	InChI=1S/C57H68N12O10/c1-31(2)50(69-56(78)48(26-35-30-63-43-16-8-5-13-39(35)43)67-53(75)45(23-32-18-20-36(70)21-19-32)65-52(74)40(59)27-49(71)72)57(79)68-47(25-34-29-62-42-15-7-4-12-38(34)42)55(77)66-46(24-33-28-61-41-14-6-3-11-37(33)41)54(76)64-44(51(60)73)17-9-10-22-58/h3-8,11-16,18-21,28-31,40,44-48,50,61-63,70H,9-10,17,22-27,58-59H2,1-2H3,(H2,60,73)(H,64,76)(H,65,74)(H,66,77)(H,67,75)(H,68,79)(H,69,78)(H,71,72)/t40-,44-,45-,46+,47+,48+,50-/m0/s1
InChI Key	QQHOFZNACVKNHK-SXVLBCBNSA-N
Isomeric SMILES	CC(C)[C@@H](C(=O)N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@H](CC7=CC=C(C=C7)O)NC(=O)[C@H](CC(=O)O)N
BoilingPoint	1555.4ºC at 760 mmHg
ShelfLife	>3 years if stored properly
Melting Point	N/A

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