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Motilin (26-47), human, porcine

Motilin (26-47), human, porcine is an endogenous motilin receptor ligand with Ki and EC50 of 2.3 nM and 0.3 nM in a Chinese hamster ovary cell line.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R1516

CAS No:52906-92-0

Synonyms/Alias:52906-92-0;Motilin (26-47), human, porcine;MOTILIN;CHEMBL411576;PML-4147-V;BDBM50143037;DA-55645;

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M.F/Formula
C120H188N34O35S
M.W/Mr.
2699.1
Sequence
One Letter Code:FVPXFXYGELQRMQEKERNKGQ
Three Letter Code:H-DL-Phe-DL-Val-DL-Pro-DL-xiIle-DL-Phe-DL-xiThr-DL-Tyr-Gly-DL-Glu-DL-Leu-DL-Gln-DL-Arg-DL-Met-DL-Gln-DL-Glu-DL-Lys-DL-Glu-DL-Arg-DL-Asn-DL-Lys-Gly-DL-Gln-OH
Application
Endogenous motilin receptor ligand (Ki = 2.3 nM) that regulates gastrointestinal motor function. Stimulates contraction of gut smooth muscle (EC50 = 1 nM) and increases pepsin release.
InChI
InChI=1S/C120H188N34O35S/c1-9-64(6)97(152-114(184)86-31-22-53-154(86)117(187)96(63(4)5)151-99(169)70(123)56-66-23-12-10-13-24-66)115(185)150-84(57-67-25-14-11-15-26-67)113(183)153-98(65(7)155)116(186)149-83(58-68-32-34-69(156)35-33-68)101(171)135-60-91(161)136-75(39-45-93(163)164)105(175)147-82(55-62(2)3)111(181)145-77(37-43-88(125)158)106(176)140-73(29-20-51-132-119(128)129)103(173)146-80(48-54-190-8)110(180)142-76(36-42-87(124)157)107(177)144-79(41-47-95(167)168)108(178)139-72(28-17-19-50-122)102(172)143-78(40-46-94(165)166)109(179)141-74(30-21-52-133-120(130)131)104(174)148-85(59-90(127)160)112(182)138-71(27-16-18-49-121)100(170)134-61-92(162)137-81(118(188)189)38-44-89(126)159/h10-15,23-26,32-35,62-65,70-86,96-98,155-156H,9,16-22,27-31,36-61,121-123H2,1-8H3,(H2,124,157)(H2,125,158)(H2,126,159)(H2,127,160)(H,134,170)(H,135,171)(H,136,161)(H,137,162)(H,138,182)(H,139,178)(H,140,176)(H,141,179)(H,142,180)(H,143,172)(H,144,177)(H,145,181)(H,146,173)(H,147,175)(H,148,174)(H,149,186)(H,150,185)(H,151,169)(H,152,184)(H,153,183)(H,163,164)(H,165,166)(H,167,168)(H,188,189)(H4,128,129,132)(H4,130,131,133)
InChI Key
LVRVABPNVHYXRT-UHFFFAOYSA-N

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