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MUC5AC-13

This glycopeptide is an N-acetyl galactosamine (GalNAc)-modified MUC5AC mucin peptide containing the single site of threonine 13 labeled with GalNAc (T*). Polypeptide N-acetylgalactosaminyltransferase (ppGaNTase) catalyzes the transfer of GalNAc from the nucleotide sugar UDP-GalNAc to threonine. The MUC5AC gene is mainly expressed in gastric and tracheo-bronchial mucosae, and some tumors.

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M.W/Mr.1704.9
SequenceOne Letter Code: GTTPSPVPTTST-T*-SAP
Three Letter Code: H-Gly-Thr-Thr-Pro-Ser-Pro-Val-Pro-Thr-Thr-Ser-Thr-Thr*-Ser-Ala-Pro-OH(Thr*=GalN aclabeled Thr)
ReferencesTen Hagen, K. et al. J. Biol. Chem. 277, 22616 (2002).
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