Murepavadin (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic for the treatment of bacterial infections caused by Pseudomonas aeruginosa. Murepavadin (TFA) targets the lipopolysaccharide transport portin D .
Peptide Library Construction and Screening
Powerful screening tools in biological and chemical research
M.F/Formula | C₇₃H₁₁₂N₂₂O₁₆.C₂HF₃O₂ |
M.W/Mr. | 1667.83 |
Sequence | One Letter Code: Cyclo(AS-d-Pro-PTWI-Dab-Orn-d-Dab-Dab-W-Dab-Dab) three Letter Code: Cyclo(Ala-Ser-d-Pro-Pro-Thr-Trp-Ile-Dab-Orn-d-Dab-Dab-Trp-Dab-Dab) |
2. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs
4. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
5. High fat diet and GLP-1 drugs induce pancreatic injury in mice
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