MV1 is an antagonist of IAP (inhibitor of apoptosis protein), leads to protein knockdown of HaloTag-fused proteins when combined with HaloTag ligand.
CAT No: 10-101-238
CAS No:1001600-54-9
Synonyms/Alias:1001600-54-9;MV1;CHEBI:47922;methyl 1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-L-prolyl-beta-phenyl-L-phenylalaninate;CHEMBL2048500;methyl (S)-2-((S)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoate;methyl (2S)-2-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3,3-diphenylpropanoate;MV1?;SCHEMBL21106842;BQB60054;EX-A4064;BDBM50546196;AKOS040742188;DA-65717;MS-30376;HY-113534;CS-0062659;G16700;EN300-22992267;Q27120849;methyl (2S)-2-{[(2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamino)propanamido]acetyl]pyrrolidin-2-yl]formamido}-3,3-diphenylpropanoate;
MV1 is a specialized carbohydrate compound recognized for its unique structural properties and versatility in scientific research. As a synthetic oligosaccharide, MV1 is designed to mimic or interact with specific biological molecules, making it a valuable tool in various experimental and analytical settings. Its stability, solubility, and ability to form specific interactions with proteins and other biomolecules have positioned it as an indispensable reagent in glycobiology, molecular biology, and biochemistry laboratories. Researchers appreciate MV1 for its reproducibility and the precise control it offers in experimental design, enabling detailed studies of carbohydrate-related mechanisms and pathways.
Glycobiology Research: MV1 plays a pivotal role in advancing glycobiology by serving as a model compound for studying carbohydrate-protein interactions. Scientists utilize it to investigate the binding affinities and specificities of lectins, antibodies, and other carbohydrate-binding proteins. By incorporating MV1 into binding assays or microarrays, researchers can elucidate the structural requirements for recognition and signaling, thereby deepening understanding of cellular communication, immune responses, and pathogen-host interactions. The insights gained from these studies contribute to the broader field of glycoscience, informing the design of new biomolecules and therapeutic strategies.
Enzyme Substrate Studies: In enzymology, MV1 functions as a substrate analog for glycosidases and glycosyltransferases, enabling precise kinetic and mechanistic investigations. Researchers employ it to dissect enzyme specificity, catalytic efficiency, and reaction mechanisms by monitoring the enzymatic modification or cleavage of MV1 under controlled conditions. Such studies are instrumental in mapping enzyme active sites, identifying key residues involved in catalysis, and developing enzyme inhibitors or modulators. The use of MV1 in this context accelerates the discovery of novel enzyme functions and the engineering of biocatalysts for synthetic biology applications.
Analytical Method Development: Analytical chemists leverage the distinctive properties of this carbohydrate compound to refine and validate detection methods for saccharides and glyco-conjugates. MV1 is incorporated as a standard or calibration reference in chromatographic, electrophoretic, or mass spectrometric analyses. Its defined structure and predictable behavior facilitate accurate quantitation, method optimization, and troubleshooting in complex sample matrices. The adoption of MV1 in analytical workflows enhances data reliability and supports high-throughput screening of carbohydrates in diverse research and industrial settings.
Cell Signaling Investigations: MV1 is instrumental in dissecting carbohydrate-mediated cell signaling pathways. Its ability to mimic natural oligosaccharides allows researchers to probe the roles of specific glycan motifs in cellular recognition, adhesion, and signal transduction. By integrating MV1 into cell-based assays, scientists can monitor downstream effects such as changes in gene expression, protein phosphorylation, or cellular migration. These studies offer valuable insights into the molecular underpinnings of development, differentiation, and disease, enabling the identification of novel signaling nodes and regulatory mechanisms.
Biomaterials Engineering: The application of MV1 extends to the development of advanced biomaterials for research and technological innovation. Its incorporation into hydrogels, nanoparticles, or surface coatings imparts bioactive properties that modulate cell behavior, enhance biocompatibility, or enable targeted delivery. Materials scientists exploit the structural versatility of MV1 to create functionalized surfaces that promote selective cell attachment or resist biofouling. These engineered materials find use in tissue engineering, biosensing, and drug delivery research, where precise control over biological interactions is essential for performance and reproducibility. By providing a reliable and customizable carbohydrate building block, MV1 continues to empower scientific discovery and innovation across multiple disciplines.
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