Myristoyl Tetrapeptide-12 is a synthetic peptide consisting of four amino acids conjugated with myristic acid. Widely utilized in cosmetic formulations, it is valued for its ability to support the appearance and feel of skin by enhancing conditioning and improving product texture. This ingredient is suitable for use in a variety of personal care applications, including facial serums, creams, and hair care products, in compliance with global cosmetic regulations.
Mechanism of Action (MOA)
Myristoyl Tetrapeptide-12 is a biomimetic signaling peptide conjugated with a myristoyl lipid chain to enhance skin penetration. Upon topical application, it interacts with skin cells by mimicking the activity of naturally occurring matrikines. This peptide can support cell–cell communication and modulate extracellular matrix-related signaling pathways, such as those involving fibronectin and integrins. These interactions may help optimize the skin’s structural environment and contribute to a balanced cellular response.
Myristoyl Tetrapeptide-12 is suitable for incorporation into a variety of cosmetic formulations.
- Facial serums and emulsions- Eye contour creams and gels- Lightweight moisturizing lotions- Leave-on facial masks- Age-defying skincare products- After-sun and soothing treatments- Specialty skin care concentrates
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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.