N-(3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methylphenyl)-4-(1-(dimethylamino)ethyl)benzamide contains aromatic, heterocyclic, and amide-bearing units that promote diverse binding interactions. The rigid framework supports modeling of planar-nonplanar complementarity. Researchers explore its electronic characteristics and steric behavior. Applications include ligand-scaffold exploration, structural chemistry, and binding-affinity modeling.
CAT No: R2655
CAS No:112199-06-1
Synonyms/Alias:N-(3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methylphenyl)-4-(1-(dimethylamino)ethyl)benzamide;112199-06-1;KETKUILYCSNHBK-UHFFFAOYSA-N;CHEMBL3685186;SCHEMBL14244627;BDBM112199;FP109502;US8623889, 197;Prepro-Atrial Natriuretic Factor (56-92) (human);Prepro-Atrial Natriuretic Factor (56-92) (human) trifluoroacetate salt;H-Glu-Val-Val-Pro-Pro-Gln-Val-Leu-Ser-Glu-Pro-Asn-Glu-Glu-Ala -Gly-Ala-Ala-Leu-Ser-Pro-Leu-Pro-Glu-Val-Pro-Pro-Trp-Thr-Gly-Glu-Val-S er-Pro-Ala-Gln-Arg-OH; H-EVVPPQVLSEPNEEAGAALSPLPEVPPWTGEVSPAQR-OH;N-(3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methylphenyl)-4-(1-(dimethylamino)ethyl) benzamide;N-(3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methylphenyl)-4-(1-(dimethylamino)ethyl)benzamide;
N-(3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methylphenyl)-4-(1-(dimethylamino)ethyl)benzamide is a sophisticated carbohydrate compound that has garnered significant interest in research and development settings due to its unique molecular architecture and versatile chemical properties. This compound features a complex aromatic framework, integrating isoquinoline and benzamide motifs, along with a cyclopropanecarboxamido group, which together contribute to its potential for diverse interactions within biological and chemical systems. The presence of both hydrophobic and hydrophilic regions within its structure enables enhanced solubility and compatibility in various organic and aqueous environments, making it a valuable candidate for advanced studies. Its design allows for targeted modifications, providing researchers with a flexible scaffold for the creation of novel derivatives or conjugates. The integration of a dimethylaminoethyl moiety further enhances its chemical reactivity and potential for functionalization, broadening the scope of its applications in both exploratory and applied research.
Medicinal Chemistry Research: N-(3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methylphenyl)-4-(1-(dimethylamino)ethyl)benzamide is frequently investigated as a lead compound or molecular probe in medicinal chemistry, particularly for its capacity to interact with complex biological targets. Its intricate aromatic system and amide functionalities allow for the exploration of structure-activity relationships, enabling scientists to identify key pharmacophores and optimize molecular interactions for enhanced binding affinity and selectivity. By serving as a foundational structure, this compound supports the development of new analogs aimed at modulating specific biochemical pathways, thereby advancing the understanding of molecular mechanisms and facilitating the identification of promising candidates for further study.
Chemical Biology Probes: In the realm of chemical biology, this benzamide derivative is utilized as a scaffold for the design and synthesis of molecular probes. Its modular structure allows for the attachment of various reporter groups, affinity tags, or reactive handles, enabling the creation of tools for the detection, isolation, or manipulation of biomolecules in complex biological samples. Researchers leverage its chemical versatility to develop probes that can elucidate protein-ligand interactions, map cellular pathways, or monitor enzymatic activities in real time. The ability to tailor its functionality makes it especially valuable for dissecting intricate biological systems and validating new targets in fundamental research.
Organic Synthesis Intermediate: The structural complexity and functional group diversity of N-(3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methylphenyl)-4-(1-(dimethylamino)ethyl)benzamide render it an excellent intermediate in multi-step organic synthesis. Chemists employ this compound as a building block for the assembly of more elaborate molecules, taking advantage of its reactive amide and aromatic sites for further derivatization. Its role as an intermediate facilitates the synthesis of structurally related analogs, heterocyclic compounds, or conjugated systems, thereby supporting the advancement of synthetic methodologies and the exploration of new chemical space.
Material Science Applications: Beyond the life sciences, this isoquinoline-based compound is explored for its potential in material science, particularly in the development of functional materials or molecular devices. The combination of aromatic rigidity and flexible substituents imparts unique electronic and photophysical properties, making it a candidate for incorporation into organic electronic materials, sensors, or supramolecular assemblies. Researchers investigate its ability to participate in π-π stacking, hydrogen bonding, or other non-covalent interactions, which can be harnessed to design innovative materials with tailored properties for specific technological applications.
Analytical Chemistry Tools: The distinct structural features of N-(3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methylphenyl)-4-(1-(dimethylamino)ethyl)benzamide also make it suitable for use as a reference standard, calibration compound, or analytical probe in various chromatographic or spectroscopic techniques. Its well-defined molecular characteristics facilitate accurate quantification, method validation, and the development of sensitive assays for the detection of related compounds or impurities. By providing a reliable benchmark, it supports the advancement of analytical methodologies in both research and quality control laboratories.
In summary, N-(3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methylphenyl)-4-(1-(dimethylamino)ethyl)benzamide stands as a versatile and valuable compound across multiple scientific disciplines. Its applications in medicinal chemistry, chemical biology, organic synthesis, material science, and analytical chemistry underscore its significance as a multifunctional tool for innovation and discovery. The compound's unique structure not only facilitates a wide array of experimental approaches but also inspires the development of new derivatives and methodologies, thereby contributing to the ongoing progress in both fundamental and applied research.
1. Emerging applications of nanotechnology for diagnosis and therapy of disease: a review
4. Immune-awakening Saccharomyces-inspired nanocarrier for oral target delivery to lymph and tumors
5. Implications of ligand-receptor binding kinetics on GLP-1R signalling
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.