NFAT Inhibitor

Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.

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ExplanationNFAT inhibitor is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation f nuclear factor of activated T cells (NFAT). It effectively blocks calcineurin binding to NFAT without disrupting other calcineurin-dependent pathways
Synonyms/AliasVIVIT peptide
SequenceOne Letter Code: MAGPHPVIVITGPHEE
Three Letter Code: Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu
AppearanceLyophilized powder
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