[Nle8,18, Tyr34] Parathyroid Hormone (1-34), human

[Nle8,18, Tyr34] Parathyroid Hormone (1-34), human features residues norleucine and tyrosine substitutions that modulate hydrophobic packing and structural stability. The modified N-terminal region retains helical propensity essential for receptor-related studies. Its sequence supports examination of structure-activity relationships. Research uses include analog evaluation, conformational profiling, and ligand-design analysis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: P03056

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cGMP Peptide
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  • CMC information required for an IND
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  • Drug master files (DMF) filing
M.F/Formula
C183H295N55O52
M.W/Mr.
4097.7
Sequence
One Letter Code: SVSEIQL-Nle-HNLGKHLNS-Nle-ERVEWLRKKLQDVHNY
three Letter Code: H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Nle-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Nle-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Tyr-OH (trifluoroacetate salt)
Source#
Synthetic

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