O-tert.Butyl-D-threonine

Name: O-tert.Butyl-D-threonine
Brand: Creative Peptides
Rating: 5 (1 reviews)

O-tert.Butyl-D-threonine is a threonine-derived amino acid derivative in which the side-chain hydroxyl is converted to an O-tert-butyl ether, retaining the amino acid backbone with both an amino group and a carboxyl group. The molecule bears a β-hydroxyl-equivalent functionality masked as a tert-butyl-protected ether, and the D stereochemical designation in the name specifies the configuration at the α-carbon while the remaining stereochemistry is defined by the threonine framework. This protected threonine analogue is used in peptide and amino acid derivative synthesis as a substrate precursor where selective side-chain protection helps control chemoselectivity during coupling and subsequent deprotection steps, and it can also serve as a defined building block for structure-activity studies requiring an ether-masked threonine side chain.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP01933

CAS No:201274-81-9

Synonyms/Alias:H-D-THR(TBU)-OH;201274-81-9;O-tert-Butyl-D-threonine;(2R,3S)-2-amino-3-(tert-butoxy)butanoicacid;D-Threonine,O-(1,1-dimethylethyl)-;O-tert.Butyl-D-threonine;O-T-BUTYL-D-THREONINE;SCHEMBL1770797;CTK5J1304;MolPort-020-004-540;ZINC8575909;AM82266;AJ-57635;AK-88973;KB-59333;SC-09893;RT-013198;ST24047352;X4320;M-2710

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M.F/Formula

C8H17NO3

M.W/Mr.

175.2

Abbr

H-D-Thr(tBu)-OH

InChI

1S/C8H17NO3/c1-5(6(9)7(10)11)12-8(2,3)4/h5-6H,9H2,1-4H3,(H,10,11)/t5-,6+/m0/s1

InChI Key

NMJINEMBBQVPGY-NTSWFWBYSA-N

Canonical SMILES

CC(C(C(=O)O)N)OC(C)(C)C

1. A possible role of tachykinin-related peptide on an immune system activity of mealworm beetle, Tenebrio molitor L

2. An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I

3. Myotropic activity of allatostatins in tenebrionid beetles

4. Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics

5. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

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